Adult cardiac surgery
Thoracic surgery
Heart failure / mechanical circulatory assist
Cardiothoracic Transplantation
Ph.D., Case Western Reserve University Graduate School of Engineering, Cleveland, OH, 1996.
M.D., Case Western Reserve University School of Medicine, Cleveland, OH, 1997.
Intern and General Surgery Resident, University of Pittsburgh Medical Center, Pittsburgh, PA, 1997-2000, 2002-2003.
Chief Resident, General Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, 2003-2004.
Research Fellow, Cardiothoracic Donor Procurement Team, University of Pittsburgh Medical Center, Pittsburgh, PA, 2000-2002.
Cardiothoracic Resident, University of Michigan Medical Center, Ann Arbor, MI, 2004-2006.
Cardiothoracic Transplant & Ventricular Assist Device Fellow, Washington University Barnes-Jewish Hospital, St. Louis, MO, 2006-2007.
Christian Hospital Northeast
11155 Dunn Road, Professional Building 1, Suite 204N
St. Louis, MO 63136
(314) 355-3003
Fax: (314) 355-0515
Extracellular matrix remodeling in heart failure and mechanical circulatory support
Mechanical circulatory assist devices and total artificial hearts
Donor organ preservation and ischemia-reperfusion injury
Implant device-centered infections
Physicochemical interactions of biomaterials with cells and proteins
Blood and biocompatibility of implant materials
Kaplon RJ, Gillinov AM, Smedira NG, Kottke-Marchant K, Wang I, Goormastic M, McCarthy PM. Vitamin K reduces bleeding in left ventricular assist device recipients. Journal of Heart and Lung Transplantation. 1999;18(4):346-350.
Siedlecki CA, Wang I, Higashi JM, Kottke-Marchant K, Marchant RE. Platelet-derived microparticles on synthetic surfaces observed by atomic force microscopy and fluorescence microscopy. Biomaterials. 1999;20:1521-1529.
Higashi JM, Wang I, Shlaes DM, Anderson JM, Marchant RE. Adhesion of Staphylococcus epidermidis and transposon mutant strains to hydrophobic polyethylene. Journal of Biomedical Materials Research. 1998;39(3):341-350.
Wang I, Kottke-Marchant K, Vargo RL, McCarthy PM. Hemostatic profiles of HeartMate ventricular assist device recipients. ASAIO Journal. 1995;41:M782-787.
Wang I, Anderson JM, Jacobs MR, Marchant RE. Adhesion of Staphylococcus epidermidis to biomedical polymers: contributions of surface thermodynamics and hemodynamic shear conditions. Journal of Biomedical Materials Research. 1995;29:485-494.
Kottke-Marchant K, Wang I, Vargo RL, McCarthy PM. Hemostatic changes after implantation of the HeartMate ventricular assist device as bridge to transplant. Thromb Haemostasis. 1995;73:1347.
Anderson JM, Boyer, Brundstedt MR, Jacobs MR, Kieswetter KM, Marchant RE, Merritt K, Rubin KR, Shlaes DM, Wang I. In vitro approaches to elucidating adhesion mechanisms of cardiovascular material-centered infections. In: Chamberlain VC and Hutchins VM, eds. Infection Control Symposium – Influences of medical device design. U.S. Department of Health and Human Services, FDA 95-4260. 1995.
Wang I, Anderson JM, Marchant RE. Platelet mediated adhesion of Staphylococcus epidermidis to hydrophobic NHLBI reference polyethylene. Journal of Biomedical Materials Research. 1993;27:1119-1128.
Wang I, Anderson JM, Marchant RE. Staphylococcus epidermidis adhesion to hydrophobic biomedical polymers is mediated by platelets. Journal of Infectious Diseases. 1993;167:329-336.
Marchant RE, Wang I. Physical and Chemical Aspects of Biomaterials Used in Humans. In: Greco RS, ed. Implantation Biology: the Host Response and Biomedical Devices. Boca Raton: CRC Press;1994:13-28.
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