Daniel Kreisel, M.D., Ph.D.

Cardiothoracic Surgery
Assistant Professor of Surgery

Board Certification:
General Surgery -- Certified
Thoracic Surgery -- Certified

Areas of Specialty and Clinical Interest:
Dr. Kreisel specializes in general thoracic surgery and lung transplantation.

Other areas of clinical interest include thoracic oncology and benign esophageal disease.

Medical School:
Mount Sinai School of Medicine, New York, N.Y., 1995

Postdoctoral Education:
Intern in General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 1995-96

Resident in General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 1996-2002

Chief Resident in General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2002-03

Ph.D., Immunology Graduate Group, University of Pennsylvania, 2002

Fellow in Cardiothoracic Surgery, Washington University in St. Louis, St. Louis, MO, 2003-05

Patients Seen At:
Center for Advanced Medicine
Jacqueline Maritz Lung Center
4921 Parkview Place, Suite B, Floor 8
St. Louis, MO 63110
(314) 454-7280

Barnes-Jewish West County Hospital
Professional Office Building One
1040 North Mason Road, 201
St. Louis, MO 63141
((314) 996-3179

Research Interest:
Transplantation immunology, tumor immunology, innate immunity and ischemia-reperfusion injury.

Awards/Honors:
2002: Jonathan E. Rhoads Research Award, University of Pennsylvania

1998: Research Fellowship, Thoracic Foundation for Research and Education

1998: Sherwood Davis & Geck Research Fellowship, Association for Academic Surgeons

1995: Alpha Omega Alpha, Lambda Chapter, Honor Medical Society

1995: Arthur H. Aufses, Sr. Prize in Surgery, Mount Sinai School of Medicine

1995: George James Award for the Best Epidemiology Study, Mount Sinai School of Medicine.

Selected or Recent Publications:
Krupnick AS, Gelman AE, Barchet W, Richardson S, Kreisel FH, Turka LA, Colonna M, Patterson GA, Kreisel D. Murine vascular endothelium activates and induces the generation of allogeneic CD4+25+Foxp3+ regulatory T cells. Journal of Immunology. 2005;175(10):6265-6270.

Kreisel D, Bailey M, Lindsay BD, Damiano RJ. A minimally invasive surgical treatment for inappropriate sinus tachycardia. Journal of Thoracic and Cardiovascular Surgery. 2005;130(2):598-599.

Krupnick AS, Kreisel D, Hope A, Bradley J, Govindan R, Meyers B. Recent advances and future perspectives in the management of lung cancer. Current Problems in Surgery. 2005;42(8):540-610.

Kreisel D, Krupnick AS, Huddleston CB. Long term outcomes and complications after pulmonary resections in the pediatric population. Seminars in Thoracic and Cardiovascular Surgery. 2004;16(3):215-219.

Kreisel D, Krasinskas AM, Krupnick AS, Balsara KR, Popma SH, Wu Z, Rosengard AM, Turka LA, Rosengard BR. Vascular endothelium does not activate CD4+ direct allorecognition in graft rejection. Journal of Immunology. 2004;173:3027-3034.

Krupnick AS, Balsara KR, Kreisel D, Riha M, Estives MS, Gelman AE, Amin KM, Rosengard BR, Flake AW. Fetal liver as a source of multilineage progenitor cells for perinatal tissue engineering. Tissue Engineering. 2004;10:723-735.

Krupnick AS, Kreisel D, Riha M, Balsara K, Rosengard BR. Myocardial tissue engineering and regeneration as a therapeutic alternative to cardiac transplantation. Current Topics in Microbiology and Immunology. 2004;280:139-165.

Krupnick AS, Zhu Z, Nguyen T, Kreisel D, Balsara KR, Lankford EB, Clark C, Levine S, Stedman H, Shrager J. Increased diaphragmatic loading by tracheal banding does not accelerate progression of muscular dystrophy in the mdx mouse. Journal of Applied Physiology. 2003;94(2):411-419.

Kreisel D, Krupnick AS, Gelman AE, Engels FH, Popma SH, Krasinskas AM, Balsara KR, Szeto WY, Turka LA, Rosengard BR. Non-hematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: an alternative mechanism of allorecognition. Nature Medicine. 2002;8(3):233-239.

Kreisel D, Krupnick AS, Balsara KR, Riha M, Gelman AE, Popma SH, Szeto WY, Turka LA, Rosengard BR. Mouse vascular endothelium activates CD8+ T lymphocytes in a B7-dependent fashion. Journal of Immunology. 2002;169(11):6154-6161.

Szeto WY, Krasinskas AM, Kreisel D, Krupnick AS, Popma SH, Rosengard BR. Depletion of recipient CD4+ but not CD8+ T lymphocytes prevents the development of cardiac allograft vasculopathy. Transplantation. 2002;73(7):1116-1122.

Kreisel D, Petrowsky H, Krasinskas AM, Krupnick AS, Szeto WY, Popma SH, McLean AD, Moore JS, Rosengard BR. The role of passenger leukocyte genotype in rejection and acceptance of rat liver allografts. Transplantation. 2002;73(9):1501-1507.

Szeto WY, Kreisel D, Karakousis GC, Pochettino A, Sterman DH, Kotloff RM, Arcasoy SM, Zisman DA, Blumenthal NP, Gallop RJ, Kaiser LR, Bavaria JE, Rosengard BR. The ue of cardiopulmonary bpass for lung transplantation does not adversely affect lung function or clinical outcome in patients with chronic obstructive pulmonary disease. Journal of Thoracic Cardiovascular Surgery. 2002;124(2):241-249.

Krasinskas AM, Kreisel D, Acker MA, Bavaria JE, Pochettino A, Kotloff RM, Arcasoy S, Blumenthal N, Kamoun M, Moore JS, Rosengard BR. CD3 monitoring of antithymocyte globulin therapy in thoracic organ transplantation. Transplantation. 2002;73(8):1339-1341.

Kreisel D, Sankaran D, Wells AD, Turka LA. Interleukin-2-mediated proliferative and survival signals are uncoupled in T lymphocytes that fail to divide after activation. American Journal of Transplantation. 2002; 2(2):120-128.

Pub Med page for Daniel Kreisel, M.D., Ph.D.

Selected or Recent Chapters:
Williams NN, Kreisel D. Bile Ductular Injuries. In: Afdhal N (ed.). Gallbladder and Biliary Tract Diseases. Marcel Dekker, Inc.;2000. Chapter 36: 823-842.

Kreisel D, Rosengard BR. Heart Transplantation. In: Norton JA, Bollinger RR, Chang AE, Lowry SF, Mulvihill SJ, Pass HI, Thompson RW (eds.). Surgery. Basic Science and Clinical Evidence. Springer-Verlag; 2000. Chapter 69: 1529-1552.

Kreisel D, Rosengard BR. Immunology and Transplantation. In: Kreisel D, Krupnick AS, Kaiser LR. (eds.). The Surgical Review: a Comprehensive Clinical and Basic Science Study Guide. Lippincott, Williams & Wilkins; 2000. Chapter 2: 37-58.

Rosato EF, Williams NN, Kreisel D, Low DW. Total Proctocolectomy in Inflammatory Bowel Disease. In: Baker RJ, Fischer JE (eds.). Mastery of Surgery. Lippincott, Williams & Wilkins; 2001. Chapter 148: 1538-1547


Books:
Kreisel D, Krupnick AS, Kaiser LR (eds.). The Surgical Review: a Comprehensive Clinical and Basic Science Study Guide. Lippincott, Williams & Wilkins; 2000.

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