G. Alexander Patterson, M.D.

Cardiothoracic Surgery
Evarts A. Graham Professor, Surgery
Chief, Division of Cardiothoracic Surgery


Appointments:
Vice president, American Association for Thoracic Surgery, 2007-2008.

Board Certification:
Thoracic Surgery -- Certified
General Surgery -- Certified
Vascular Surgery -- Certified

Areas of Specialty and Clinical Interest:
Dr. Patterson specializes in lung transplantation, esophageal cancer, lung cancer, emphysema, thoracic surgery and lung volume reduction.

His practice includes surgery for lung cancer, esophageal cancer and esophageal disease, myasthenia gravis, lung transplantation and lung volume reduction surgery.

Medical School:
Queen's University, 1974

Postdoctoral Education:
Residency: General Surgery Queen's University ,1974-78
University of Toronto-Vascular Surgery, 1978-79
University of Toronto-Thoracic Surgery, 1979-81

Fellowships: John Hopkins-Pulmonary Fellow,1981-82
University of Toronto-Department of Surgery Lecturer, 1982-84

Patients Seen At:
Center for Advanced Medicine
Jacqueline Maritz Lung Center
4921 Parkview Place, Suite B, Floor 8
St. Louis, MO 63110
(314) 362-6025
Fax: (314) 747-4087

Barnes-Jewish West County Hospital
Professional Office Building One
1040 North Mason Road, 201
St. Louis, MO 63141
((314) 996-3179

Patient Appointments:
1-888-287-8741 or (314) 362-6025

Research Interest:
Lung allograft reperfusion injury

Funding:
National Institutes of Health

Awards/Honors:
Listed in Best Doctors in America (Best Doctors, Inc.), 2007

Listed in America's Top Doctors, seventh edition, Castle Connolly Medical Ltd., 2007

Selected or Recent Publications:
Hachem RR, Yusen RD, Chakinala MM, Meyers BF, Lynch JP, Aloush AA, Patterson GA, Trulock EP. A randomized controlled trial of tacrolimus versus cyclosporine after lung transplantation. Journal of Heart and Lung Transplantation. 2007;26(10):1012-1018.

Ray M, Dharmarajan S, Freudenberg J, Zhang W, Patterson GA. Expression profiling of human donor lungs to understand primary graft dysfunction after lung transplantation. American Journal of Transplantation. 2007;7(10):2396-2405.

Okazaki M, Gelman AE, Tietjens JR, Ibricevic A, Kornfeld CG, Huang HJ, Richardson SB, Lai J, Garbow JR, Patterson GA, Krupnick AS, Brody SL, Kreisel D. Maintenance of airway epithelium in acutely rejected orthotopic vascularized mouse lung transplants. American Journal of Respiratory Cell and Molecular Biology. 2007;37(6):625-630.

Schena S, Crabtree TD, Zoole JB, Patterson GA. Intralobar pulmonary sequestration associated with an aneurysmal aberrant aortic branch. Journal of Thoracic and Cardiovascular Surgery. 2007;134(2):535-536.

Okazaki M, Krupnick AS, Kornfeld CG, Lai JM, Ritter JH, Richardson SB, Huang HJ, Das NA, Patterson GA, Gelman AE, Kreisel D. A mouse model of orthotopic vascularized aerated lung transplantation. American Journal of Transplantation. 2007;7(6):1672-1679.

Okazaki M, Kreisel F, Richardson SB, Kreisel D, Krupnick AS, Patterson GA, Gelman AE. Sphingosine 1-phosphate inhibits ischemia reperfusion injury following experimental lung transplantation. American Journal of Transplantation. 2007;7(4):751-758.

Bharat A, Narayanan K, Street T, Fields RC, Steward N, Aloush A, Meyers B, Schuessler R, Trulock EP, Patterson GA, Mohanakumar T. Early posttransplant inflammation promotes the development of alloimmunity and chronic human lung allograft rejection. Transplant. 2007;83:150-158.

Lau CL, Hoganson DM, Meyers BF, Damiano RJ, Patterson GA. Use of an apical heart suction device for exposure in lung transplantation. Annals of Thoracic Surgery. 2006;81(4):1524-1525.

Tyner JW, Kim EY, Ide K, Pelletier MR, Roswit WT, Morton JD, Battaile JT, Patel AC, Patterson GA, Castro M, Spoor MS, You Y, Brody SL, Holtzman MJ. Blocking airway mucous cell metaplasia by inhibiting EGFR anti-apoptosis and IL-13 transdifferentiation signals. Journal of Clinical Investigation. 2006;116(2):309-321.

Kozower BD, Sweet SC, de la Morena M, Schuler P, Guthrie TJ, Patterson GA, Gandhi SK, Huddleston CB. Living donor lobar grafts improve pediatric lung retransplantation survival. Journal of Thoracic and Cardiovascular Surgery. 2006;131:1142-1147.

Smith MA, Battafarano RJ, Meyers BF, Zoole JB, Cooper JD, Patterson GA. Prevalence of benign disease in patients undergoing resection for suspected lung cancer. Annals of Thoracic Surgery. 2006;81:1824-1829.

Hachem RR, Yusen RD, Chakinala MM, Aloush AA, Patterson GA, Trulock EP. Thrombotic microangiopathy after lung transplantation. Transplant. 2006;81:57-63.

Smith MA, Patterson GA, Cooper JD. Dysphagia in the young male: The ringed esophagus. Annals of Thoracic Surgery. 2006;81:354-356.

Kuo E, Bharat A, Goers T, Chapman W, Street T, Lu W, Walter M, Patterson GA, Mohanakumar T. Respiratory viral infection in obliterative airway disease following orthotopic tracheal transplant. Annals of Thoracic Surgery. 2006;82:1043-1050.

Kuo E, Bharat A, Shih J, Street T, Norris J, Liu W, Walter M, Patterson GA, Mohanakumar T. Role of airway epithelial injury in murine orthotopic tracheal allograft rejection. Annals of Thoracic Surgery. 2006;82(4):1126-1133.
Pub Med page for G. Alexander Patterson, M.D.

Academic Office:
Barnes - Jewish Hospital
One Barnes-Jewish Hospital Plaza
Suite 3108 Queeny Tower
St. Louis, MO 63110
314-362-6025

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