Charles B. Huddleston, M.D.

Cardiothoracic Surgery
Professor of Surgery
Cardiothoracic Surgeon-in-Chief, St. Louis Children' s Hospital


Board Certification:
General Surgery--Certified
Thoracic Surgery--Certified

Areas of Specialty and Clinical Interest:
Dr. Huddleston specializes in pediatric cardiothoracic surgery, cardiac surgery and cardiothoracic surgery.

Other areas of clinical interest include pediatric heart transplantation, pediatric lung transplantation, adults with congenital heart disease, and repair of pectus excavatum and carinatum.

Medical School:
Vanderbilt University School of Medicine, 1978

Postdoctoral Education:
Internship - Internal medicine, Vanderbilt University Medical Center, 1978-79
Residency - General Surgery, Vanderbilt University Medical Center, 1979-1986; Cardiothoracic Surgery, Vanderbilt University Medical Center, 1986-1988
Fellowship - Pediatric Cardiac Surgery, Hospital for Sick Children, Great Ormond Street, London, England, 1988-89.

Patients Seen At:
St. Louis Children's Hospital
One Children's Place, 5S50
St. Louis, MO 63110
(314) 454-6165

Patient Appointments:
(314) 454-6165

Hospital Affiliations:
Barnes-Jewish Hospital
Shriner's Hospital for Children
St. Louis Children's Hospital

Research Interest:
Cardiac arrhythmias following the Fontan procedure.

Awards/Honors:
2007, Listed in Best Doctors in America (Best Doctors, Inc.)

2007, Listed in America's Top Doctors, seventh edition, Castle Connolly Medical Ltd.

Selected or Recent Publications:
Choong CK, Haddad FJ, Huddleston CB, Bell J, Guthrie TJ, Mendeloff EN, Schuler P, De la Morena M, Sweet SC. Role of open lung biopsy in lung transplant recipients in a single children's hospital: a 13-year experience. Journal of Thoracic and Cardiovascular Surgery. 2006;131(1):204-208.

Choong CK, Sweet SC, Zoole JB, Guthrie TJ, Mendeloff EN, Haddad FJ, Schuler P, De la Morena M, Huddleston CB. Bronchial airway anastomotic complications after pediatric lung transplantation: incidence, cause, management, and outcome. Journal of Thoracic and Cardiovascular Surgery. 2006;131(1):198-203.

Choong CK, Hu DZ, Huddleston CB. Pulmonary segmental venous infarction after living-donor lobar lung transplantation. Journal of Thoracic and Cardiovascular Surgery. 2005 Sep;130(3):919-921.

Danziger-Isakov LA, Sweet S, Delamorena M, Huddleston CB, Mendeloff E, Debaun MR. Epidemiology of bloodstream infections in the first year after pediatric lung transplantation. Pediatric Infectious Disease Journal. 2005;24(4):324-330.

Choong CK, Sweet SC, Guthrie TJ, Mendeloff EN, Haddad FJ, Schuler P, De La Morena M, Huddleston CB. Repair of congenital heart lesions combined with lung transplantation for the treatment of severe pulmonary hypertension: a 13-year experience. Journal of Thoracic and Cardiovascular Surgery. 2005;129(3):661-669.

Nicolas RT, Hills C, Moller JH, Huddleston CB, Johnson MC. Early outcome after Glenn shunt and Fontan palliation and the impact of operation during viral respiratory season: analysis of a 19-year multi-institutional experience. Annals of Thoracic Surgery. 2005;79(2):613-617; discussion 617.

Huddleston CB. Pectus excavatum. Seminars in Thoracic and Cardiovascular Surgery. 2004;16(3):225-232.

Kreisel D, Krupnick AS, Huddleston CB. Outcomes and late complications after pulmonary resections in the pediatric population. Seminars in Thoracic and Cardiovascular Surgery. 2004;16(3):215-219.

Huddleston CB. Mediastinal wound infections following pediatric cardiac surgery. Seminars in Thoracic and Cardiovascular Surgery. 2004;16(1):108-112.

Huang J, Trinkaus K, Huddleston CB, Mendeloff EN, Spray TL, Canter CE. Risk factors for primary graft failure after pediatric cardiac transplantation: importance of recipient and donor characteristics. Journal of Heart and Lung Transplantation 2004;23(6):716-722.

McOmber D, Ibrahim J, Lublin DM, Saffitz JE, Ong-Simon C, Mendeloff EN, Huddleston CB, Canter CE. Non-ischemic left ventricular dysfunction after pediatric cardiac transplantation: treatment with plasmapheresis and OKT3. Journal of Heart and Lung Transplantation. 2004;23(5):552-557.

Hamvas A, Nogee LM, White FV, Schuler P, Hackett BP, Huddleston CB, Mendeloff EN, Hsu FF, Wert SE, Gonzales LW, Beers MF, Ballard PL. Progressive lung disease and surfactant dysfunction with a deletion in surfactant protein C gene. American Journal of Respiratory Cell and Molecular Biology. 2004;30(6):771-776. Epub 2003 Dec 4.

Danziger-Isakov LA, DelaMorena M, Hayashi RJ, Sweet S, Mendeloff E, Schootman M, Huddleston CB, DeBaun MR. Cytomegalovirus viremia associated with death or retransplantation in pediatric lung-transplant recipients. Transplantation. 2003 May 15;75(9):1538-1543.

Huddleston CB. Have we met the expectations of heart and lung transplantation in children? Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2003;6:164-170.

Pechet TV, de le Morena M, Mendeloff EN, Sweet SC, Shapiro SD, Huddleston CB. Lung transplantation in children following treatment for malignancy. Journal of Heart and Lung Transplantation. 2003;22(2):154-160.

Pub Med page for Charles B. Huddleston, M.D.

Selected or Recent Chapters:
Huddleston, CB: Pediatric Heart Transplantation. In: Kaiser LR, Krou IL, Spray TL, eds. Mastery of Cardiothoracic Surgery. Philadelphia: Lippincott-Raven, 1997:894-915.

Academic Office:
St. Louis Children's Hospital
One Children's Place, Suite 5S50
St. Louis, MO 63110
(314) 454-6165

Visit the Physicians site for full information
about your outpatient or inpatient visit.
* Patient resources* Facilities
* Financial services* Your health record
* Maps* Find a WU Physician
* Lodging